Prolonged calcium influx after termination of light-induced calcium release in invertebrate photoreceptors

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Prolonged calcium influx after termination of light-induced calcium release in invertebrate photoreceptors

In microvillar photoreceptors, light stimulates the phospholipase C cascade and triggers an elevation of cytosolic Ca2+ that is essential for the regulation of both visual excitation and sensory adaptation. In some organisms, influx through light-activated ion channels contributes to the Ca2+ increase. In contrast, in other species, such as Lima, Ca2+ is initially only released from an intracel...

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Calcium-independent, cGMP-mediated light adaptation in invertebrate ciliary photoreceptors.

Calcium is thought to be essential for adaptation of sensory receptor cells. However, the transduction cascade of hyperpolarizing, ciliary photoreceptors of the scallop does not use IP3-mediated Ca release, and the light-sensitive conductance is not measurably permeable to Ca2+. Therefore, two typical mechanisms that couple the light response to [Ca]i changes seem to be lacking in these photore...

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Calcium-induced calcium release

How are calcium levels increased within cells? Increases in intracellular calcium arise through either calcium influx across the plasma membrane or release from intracellular calcium stores, which is usually either the endoplasmic reticulum (ER) or, in muscle, the sarcoplasmic reticulum (SR). Release of calcium from the ER/SR is activated by a variety of second messengers, such as inositol 1,4,...

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Calcium-induced release of calcium

FABIATO, ALEXANDRE. Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. Am. J. Physiol. 245 (Cell Physiol. 14): CLC14, 1983.-The hypothesis of a Ca2+-induced Ca2+ release (CICR) from the sarcoplasmic reticulum (SR) is supported by experiments done in skinned cardiac cells (sarcolemma removed by microdissection). According to this hypothesis, the transsarcolemmal Ca2+ inf...

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Calcium-induced release of calcium

FABIATO, ALEXANDRE. Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. Am. J. Physiol. 245 (Cell Physiol. 14): CLC14, 1983.-The hypothesis of a Ca2+-induced Ca2+ release (CICR) from the sarcoplasmic reticulum (SR) is supported by experiments done in skinned cardiac cells (sarcolemma removed by microdissection). According to this hypothesis, the transsarcolemmal Ca2+ inf...

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ژورنال

عنوان ژورنال: Journal of General Physiology

سال: 2009

ISSN: 1540-7748,0022-1295

DOI: 10.1085/jgp.200910214